Caro C G, Dumoulin C L, Graham J M, Parker K H, Souza S P
Centre for Biological and Medical Systems, Imperial College of Science, Technology, and Medicine, London, U.K.
J Biomech Eng. 1992 Feb;114(1):147-9. doi: 10.1115/1.2895439.
The blood flow in arteries affects both the biology of the vessels and the development of atherosclerosis. The flow is three-dimensional, unsteady, and difficult to measure or to model computationally. We have used phase-shift-based magnetic resonance angiography to image and measure the flow in the common carotid arteries of a healthy human subject. There was curvature of the vessels and thin-slice dynamic flow imaging showed evidence of the presence of secondary motions. Flexing the cervical spine straightened the vessels and reduced the asymmetry of the flow.
动脉中的血流既影响血管生物学,也影响动脉粥样硬化的发展。这种血流是三维的、不稳定的,并且难以测量或通过计算建模。我们使用基于相移的磁共振血管造影术对一名健康人类受试者的颈总动脉血流进行成像和测量。血管存在弯曲,薄层动态血流成像显示存在二次运动的迹象。弯曲颈椎可使血管变直并减少血流的不对称性。