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[Histocompatibility antigens (HLA) in children with lipoid nephrosis].

作者信息

Zwolińska D, Morawska Z, Makulska I, Dmochowska D, Jaśniak K, Morawski A

机构信息

Katedry i Kliniki Nefrologii Pediatrycznej AM we Wrocławiu.

出版信息

Pol Tyg Lek. 1992;47(31-33):671-2.

PMID:1492032
Abstract

Actual knowledge on the HLA relationship with the primary glomerulopathies, with particular reference to steroid - sensitive nephrosis of childhood, is surveyed. Occurrence of HLA B-8 and B-35 in this nephropathy has been investigated. The studies involved 47 patients aged between 3 and 15 years and 117 healthy children from Lower Silesian region. It has been showed, that HLA B-8 is present more frequently in sick children, than in healthy controls. The situation is reverse in case of HLA B-35 antigen. However, the difference is statistically insignificant. A probability of the lipid nephrosis sensitivity to corticosteroids can not be predicted on the base of the presence of these HLA antigens.

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