Greenberg J, Schnell D, Conlon R
Behavioral and Prevention Research Branch, Centers for Disease Control, Atlanta, GA 30333.
Sex Transm Dis. 1992 Nov-Dec;19(6):346-50.
The impact of crack use on syphilis intervention was investigated by reviewing records of persons diagnosed with early syphilis when voluntarily attending County Health Department clinics in Detroit, Michigan and Dallas, Texas between August 1989 and August 1990. The sample was stratified and data were analyzed using multivariate techniques. Compared with men who did not use crack, male crack users were more likely to report having four or more sexual partners during their critical period for acquiring or passing on infection (odds ratio, OR = 4.33; 95% confidence interval, CI = 2.08, 8.99). Among men, having a large number of sexual partners during this period was associated with a lower percentage of contacts being examined (OR = 11.8; 95% CI = 2.91, 47.5). Among women, having four or more sexual partners during their critical period and a lower partner examination rate were both associated with crack use; crack use was strongly associated with exchanging sex for money or drugs. We conclude that crack use has the largest impact on syphilis intervention through its association with having large numbers of sexual partners.
通过查阅1989年8月至1990年8月期间在密歇根州底特律市和得克萨斯州达拉斯市自愿前往县卫生部门诊所就诊的早期梅毒确诊患者的记录，研究了吸食强效纯可卡因对梅毒干预措施的影响。样本进行了分层，并使用多变量技术对数据进行了分析。与不吸食强效纯可卡因的男性相比，吸食强效纯可卡因的男性在感染或传播感染的关键时期更有可能报告有四个或更多性伴侣（优势比，OR = 4.33；95%置信区间，CI = 2.08，8.99）。在男性中，在此期间有大量性伴侣与接受检查的性伴侣比例较低相关（OR = 11.8；95%CI = 2.91，47.5）。在女性中，在关键时期有四个或更多性伴侣以及较低的性伴侣检查率均与吸食强效纯可卡因有关；吸食强效纯可卡因与以性换取金钱或毒品密切相关。我们得出结论，吸食强效纯可卡因通过与大量性伴侣相关联，对梅毒干预措施产生了最大影响。
