Pallangyo K J
Department of Medicine, Faculty of Medicine, Muhimbili Medical Centre, Dar es Salaam, Tanzania.
Trop Doct. 1992;22 Suppl 1:35-41;60. doi: 10.1177/00494755920220S107.
Cutaneous manifestations are common in patients with HIV infection and tend to be more frequent as immunodeficiency progresses. In the initial stage of HIV infection a transient maculopapular-rash may appear. During the otherwise asymptomatic phase that follows, patients may develop seborrhoeic dermatitis, persistent genital ulcer disease, pruritic papular eruption and/or a variety of scaling dermatoses. The most frequent skin tumour associated with HIV disease is Kaposi's sarcoma. Skin manifestations of adverse reactions to a variety of drugs occur more frequently in patients with HIV disease than in immunocompetent patients. In general most skin diseases that occur in association with HIV disease respond well to standard treatment regimens. However relapses, and/or recurrences are frequent in this group of patients.
皮肤表现在HIV感染患者中很常见,并且随着免疫缺陷的进展往往会更频繁出现。在HIV感染的初始阶段,可能会出现一过性斑丘疹。在随后的无症状阶段,患者可能会出现脂溢性皮炎、持续性生殖器溃疡病、瘙痒性丘疹疹和/或多种鳞屑性皮肤病。与HIV疾病相关的最常见皮肤肿瘤是卡波西肉瘤。与免疫功能正常的患者相比,HIV疾病患者中各种药物不良反应的皮肤表现更为常见。一般来说,大多数与HIV疾病相关的皮肤病对标准治疗方案反应良好。然而,这组患者中复发和/或再发很常见。