DUGAN D J
Calif Med. 1952 Apr;76(4):273-5.
Newer surgical and anesthetic techniques and the use of streptomycin and para-aminosalicylic acid (PAS) have made possible increased success in pulmonary resection for tuberculosis. Especially in early cases, however, bed rest and pneumothorax or pneumoperitoneum should be given adequate trial before resection is decided upon. In all cases a thorough bronchoscopic examination should be made first and the findings carefully evaluated. Pulmonary resection may be advisable for lesions of certain kinds which do not respond well to thoracotomy; for lesions which have not responded to trial of other methods; for a lung destroyed by tuberculosis; and in cases of active disease in an unexpanded lung. The experience of the author and of others emphasizes the importance of correct postoperative care. Since tuberculosis is rarely limited to the resected area, at least six months' rest in bed under medical supervision is necessary to permit cure of residual disease. Streptomycin with PAS is particularly valuable in the postoperative period; therefore indiscriminate use of it in earlier treatment should be avoided lest resistance develop.
更新的外科手术和麻醉技术以及链霉素和对氨基水杨酸（PAS）的使用，使得肺结核肺切除术的成功率得以提高。然而，尤其是在早期病例中，在决定进行切除术之前，应充分尝试卧床休息和气胸或气腹治疗。在所有病例中，首先都应进行全面的支气管镜检查，并仔细评估检查结果。对于某些对开胸手术反应不佳的病变；对其他治疗方法试验无反应的病变；被结核破坏的肺；以及未扩张肺中有活动性疾病的病例，肺切除术可能是可取的。作者及其他人的经验强调了正确术后护理的重要性。由于结核病很少局限于切除区域，因此需要在医疗监督下至少卧床休息六个月，以使残留疾病得以治愈。链霉素与PAS在术后阶段特别有价值；因此，应避免在早期治疗中不加区别地使用，以免产生耐药性。
