Van Poppel H, Ameye F, Oyen R, Van De Voorde W, Baert L
University Hospital, Katholieke Universiteit Leuven, Belgium.
Acta Urol Belg. 1992;60(3):73-82.
Sixty-eight patients who underwent radical prostatectomy without or after neo-adjuvant hormonotherapy for B2 or C stage prostate cancer were evaluated as concerned to the ease of the surgical procedure. Although it is difficult to assess this parameter, we experienced more difficulties and blood loss was higher in patients who had preoperative hormonal deprivation. Ongoing randomized trials could demonstrate an oncological benefit of neo-adjuvant hormonotherapy before radical prostatectomy. This eventual benefit will have to be balanced against an increased surgical difficulty.
68例接受根治性前列腺切除术的患者，他们在B2或C期前列腺癌新辅助激素治疗前或后进行了手术，评估了手术操作的难易程度。虽然很难评估这个参数，但我们发现，术前接受激素剥夺治疗的患者手术难度更大，失血量也更多。正在进行的随机试验可能会证明新辅助激素治疗在根治性前列腺切除术之前的肿瘤学益处。这种最终的益处必须与增加的手术难度相权衡。
