Gologorskiĭ V A, Bagdat'ev V E, Gel'fand B R, Lapshina I Iu, Nistratov S L
Anesteziol Reanimatol. 1992 Sep-Dec(5-6):31-3.
Nine patients with adult respiratory distress syndrome, stage III, secondary to diffuse peritonitis have been examined. The patients were subject to pulmonary artery and aorta catheterization. Cardiac output, extravascular water in the lungs, the extent of pulmonary shunting were determined; pulmonary artery and aortic pressure were measured. O2 transport parameters, pulmonary capillary pressure (Pc), pressure gradient (Pc-COP) were calculated and arterial and venous blood gases as well as colloid-osmotic pressure (COP) were analysed. Selective hypotension in the pulmonary circulation was performed using an infusion of nitroglycerin solution. Despite differences in the response of patients with ARDS to nitroglycerin, when the drug was injected with optimal positive end-expiratory pressure, it promoted an increase in O2 delivery, normalization of pulmonary hemodynamics and a decrease in extravascular pulmonary water.
对9例继发于弥漫性腹膜炎的Ⅲ期成人呼吸窘迫综合征患者进行了检查。这些患者接受了肺动脉和主动脉插管。测定了心输出量、肺血管外水分、肺分流程度；测量了肺动脉和主动脉压力。计算了氧输送参数、肺毛细血管压力（Pc）、压力梯度（Pc-COP），并分析了动脉和静脉血气以及胶体渗透压（COP）。通过输注硝酸甘油溶液实现肺循环的选择性低血压。尽管成人呼吸窘迫综合征患者对硝酸甘油的反应存在差异，但当在最佳呼气末正压下注射该药物时，它促进了氧输送的增加、肺血流动力学的正常化以及肺血管外水分的减少。
