Cerdá Nicolás M
Departamento de Patología, Hospital Clínico Universitario, Facultad de Medicina, Valencia.
Arch Neurobiol (Madr). 1992 Nov-Dec;55(6):256-61.
In this study we analyzed the morphologic and ultrastructural characteristics of the psammoma bodies in ten meningiomas of different histologic subtypes, characterizing the components of the psammoma body and the elements of the tumor, such as the capillaries and degenerative cells that have been classically considered as initiators of the formation of these calcareous is structures. The discussion considers the diagnostic interest of psammoma bodies in central nervous system tumors, as well as its histogenesis. The different points of view explaining biological mineralization in other territories of the organism are analyzed, as well as the formation of psammoma bodies, comparing the morphologic data obtained in this study. It is concluded that the mineralization of the psammoma bodies is induced principally by the collagen fibers synthesized by the meningocytes and that the form of mineralization is spherical and growth is radial, controlled by the tumoral cells.
在本研究中，我们分析了10例不同组织学亚型脑膜瘤中砂粒体的形态学和超微结构特征，描述了砂粒体的组成成分以及肿瘤的构成要素，如传统上被认为是这些钙质结构形成起始因素的毛细血管和退变细胞。讨论内容涉及砂粒体在中枢神经系统肿瘤中的诊断意义及其组织发生。分析了关于机体其他部位生物矿化的不同观点，以及砂粒体的形成，并比较了本研究中获得的形态学数据。得出的结论是，砂粒体的矿化主要由脑膜细胞合成的胶原纤维诱导，矿化形式为球形，生长呈放射状，受肿瘤细胞控制。
