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Analgesic potency and side action liability in man of heptazone, WIN 1161-2, 6-methyl dihydromorphine, Metopon, levo-isomethadone and pentobarbital sodium, as a further effort to refine methods of evaluation of analgesic drugs.

作者信息

KEATS A S, BEECHER H K

出版信息

J Pharmacol Exp Ther. 1952 Jun;105(2):109-29.

PMID:14928215
Abstract
摘要

相似文献

1
Analgesic potency and side action liability in man of heptazone, WIN 1161-2, 6-methyl dihydromorphine, Metopon, levo-isomethadone and pentobarbital sodium, as a further effort to refine methods of evaluation of analgesic drugs.
J Pharmacol Exp Ther. 1952 Jun;105(2):109-29.
2
Biliary and small intestinal spasm due to synthetic analgesics methadone and methyldihydromorphinone (metopon).合成镇痛药美沙酮和甲基二氢吗啡酮(美托酮)引起的胆道和小肠痉挛。
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[The new central analgesics].[新型中枢性镇痛药]
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Pharmacology of metopon and other new analgesic opium derivatives.美托酮及其他新型镇痛性阿片衍生物的药理学
Ann N Y Acad Sci. 1948 Nov 1;51(Art 1):51-8. doi: 10.1111/j.1749-6632.1948.tb27250.x.
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Novel analgesics and molecular rearrangements in the morphine-thebaine group. XVI. Some derivatives of 6,14-endo-etheno-7, 8-dihydromorphine.
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A comparison of the actions of meperidine, Nu-1196, methadone, morphine, Nu-2206, and metopon upon the intestine and uterus.哌替啶、Nu - 1196、美沙酮、吗啡、Nu - 2206及美托酮对肠道和子宫作用的比较。
J Pharmacol Exp Ther. 1950 Jul;99(3):317-24.
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Pharmacological characterization of dihydromorphine, 6-acetyldihydromorphine and dihydroheroin analgesia and their differentiation from morphine.
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Uptake of etorphine and dihydromorphine after sublingual and intramuscular administration.舌下给药和肌肉注射后埃托啡和二氢吗啡的吸收情况。
Eur J Pharmacol. 1969 Sep;7(3):328-32. doi: 10.1016/0014-2999(69)90100-9.
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Heterogeneity of opioid receptor binding in brain slices.
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Synthesis and pharmacological studies of 2'-sulphonyl[3-(3H-2,4-disubstituted-1,5-benzodiazepino)]-2,5-dimethyl-6,7-benzomorphans.2'-磺酰基[3-(3H-2,4-二取代-1,5-苯并二氮杂卓)]-2,5-二甲基-6,7-苯并吗啡烷的合成及药理研究
Pharmazie. 1982 Mar;37(3):176-7.

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Kappa opioids and the modulation of pain.κ 阿片类物质与疼痛的调制。
Psychopharmacology (Berl). 2010 Jun;210(2):109-19. doi: 10.1007/s00213-010-1819-6. Epub 2010 Apr 7.
2
A comparative study of five analgesics.五种镇痛药的比较研究。
Can Anaesth Soc J. 1962 Mar;9:131-42. doi: 10.1007/BF03021255.
3
Synthetic substances with morphine-like effect: clinical experience; potency, side-effects, addiction liability.具有吗啡样作用的合成物质:临床经验;效能、副作用、成瘾倾向。
Bull World Health Organ. 1957;17(4-5):569-863.
4
Synthetic substances with morphine-like effect; relationship between analgesic action and addiction liability, with a discussion of the chemical structure of addiction-producing substances.具有吗啡样作用的合成物质;镇痛作用与成瘾倾向之间的关系,并对成瘾性物质的化学结构进行讨论。
Bull World Health Organ. 1956;14(3):353-402.
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A guide to the pharmacology of placebos.安慰剂药理学指南。
Can Med Assoc J. 1983 Apr 15;128(8):921-5.