Fernández-Nogueras F J, Fernández-Nogueras V, Esquivias López-Cuervo J J
Servicio de Otorrinolaringología, Hospital Virgen de las Nieves, Granada.
Acta Otorrinolaringol Esp. 1992 Sep-Oct;43(5):311-3.
Microvascular invasion by carcinoma cells is one of the first steps for the potential development of metástasis. The presence of squamous cell carcinoma within capillaries and/or venules in the immediate vicinity of primary lesions of the oral cavity and oropharynx may be related to regional lymph node metastasis. To evaluate this possibility in laryngeal carcinomas we have reviewed the histopathologic features of 48 cases of this type of tumor with simultaneous surgical treatment of the primary neoplasms and the neck. In our opinion the histologic finding of such invasion is not pathognomonic for establishment of regional metástasis in epidermoid carcinoma of the larynx.
癌细胞的微血管侵犯是转移潜在发展的首要步骤之一。在口腔和口咽原发性病变紧邻区域的毛细血管和/或小静脉内存在鳞状细胞癌可能与区域淋巴结转移有关。为了评估喉癌中的这种可能性，我们回顾了48例此类肿瘤的组织病理学特征，同时对原发性肿瘤和颈部进行了手术治疗。我们认为，这种侵犯的组织学发现对于喉表皮样癌区域转移的确定并非具有诊断意义。
