Occurrence of intraportally-infused urea-15N in the urine of domestic fowl.

1. Measurements were made in situ to determine the occurrence of intraportally infused urea-15N in ureteral urine of the fowl. 2. Of the total amount of infused urea-15N, 15% was excreted intact into the urine (90% of urinary total 15N) whereas 9% remained unchanged in the blood (78% of blood non-protein-15N). 3. The proportions of non-protein-15N in the blood, liver and kidney were 12, 3 and 1%, respectively of the infused 15N. Protein-15N was 3% of that infused in blood and much less in liver and kidney. 4. About 1% of the infused 15N was observed in the urinary uric acid, and 3% of the infused 15N in non-protein N, other than urea, ammonia and glutamine amide N, of blood and liver. 5. No appreciable amounts of 15N were present in ammonia and glutamine amide N of blood, liver or kidney and in uric acid of liver or kidney. 6. The caecal contents contained about 1% of the infused 15N with 15% of this as ammonia-15N. 7. It is concluded that intraportal urea is mostly excreted unchanged into ureteral urine of the fowl.