HEWITT W L
Calif Med. 1952 May;76(5):319-24.
Since the fusospirochetal group of bacteria are the commonest etiologic agents in abscess of the lung, aqueous crystalline penicillin is the agent of first choice in the majority of cases. Streptomycin is indicated for a small group of cases in which Klebsiella is the etiologic agent. Aureomycin, chloramphenicol or terramycin may produce an excellent therapeutic response either initially or after therapeutic failure with penicillin. Administration of antibiotics by inhalation should be carried out in conjunction with systemic forms of treatment. In the treatment of bronchiectasis, the antibiotics are most useful in the control of acute exacerbations of pulmonary infection which punctuate the course of this disease.
由于梭形螺旋体菌群是肺脓肿最常见的病原体，在大多数病例中，水溶性结晶青霉素是首选药物。链霉素适用于一小部分以克雷伯菌为病原体的病例。金霉素、氯霉素或土霉素在初始治疗时或青霉素治疗失败后可能会产生良好的治疗效果。吸入抗生素应与全身治疗方式联合进行。在支气管扩张症的治疗中，抗生素在控制贯穿该病病程的肺部感染急性加重方面最为有用。
