Titenko-Holland N V, Kowalska A
National Research Centre of Medical Genetics AMS, Moscow, Russia.
Hum Hered. 1992;42(6):384-6. doi: 10.1159/000154102.
alpha-1-antitrypsin (PI) subtypes were studied in Poles and Russians. The frequencies of the PI alleles were similar in the two populations, with the exception of the Z allele, whose frequency was significantly lower in Poles. The M3 allele frequency, which is highly heterogeneous in European populations, has medium frequencies in Poles and Russians.
在波兰人和俄罗斯人中研究了α1-抗胰蛋白酶(PI)亚型。除了Z等位基因外,这两个群体中PI等位基因的频率相似,Z等位基因在波兰人中的频率显著较低。M3等位基因频率在欧洲人群中高度异质,在波兰人和俄罗斯人中处于中等频率。