Minh H N, Belaisch J, Smadja A
Service central d'Anatomie et de Cytologie pathologiques, Hôpital Nord, CHRU, Amiens.
Presse Med. 1992 Nov 21;21(39):1862-7.
In the human embryo, sex is all in the genes. Later on, the male and female sexual characters, which are products of the expression of all individual genomes, differentiate men from women. In this paper, the embryogenesis and morphology of true hermaphroditism and male pseudo-hermaphroditism are studied. These are intersexual states determined by errors in genital programme transmission. A relationship is established between the biochemical identification of substances secreted by the testis and the evolution of sexual characters. The genesis of sexual abnormalities according to the stage when the testicular deficit appears is envisaged. The clinical, anatomical, histological and biochemical aspects of these intersexual states are described.
在人类胚胎中,性别完全由基因决定。后来,男性和女性的性征作为所有个体基因组表达的产物,将男性与女性区分开来。本文研究了真两性畸形和男性假两性畸形的胚胎发生及形态学。这些是由生殖程序传递错误所决定的两性畸形状态。在睾丸分泌物质的生化鉴定与性征演变之间建立了一种关系。设想了根据睾丸缺陷出现阶段的性异常发生情况。描述了这些两性畸形状态的临床、解剖、组织学和生化方面。