[与玫瑰花结现象相关的淋巴细胞分子。抗淋巴细胞血清对T（CD2 + E2 +）和B（CD2 - E2 +）淋巴细胞的不同作用]
[Lymphocytic molecules implicated in rosette phenomenon. Differential effect of antilymphocyte serum on T (CD2+E2+) and B (CD2-E2+) lymphocytes].
作者信息
Ticchioni M, Bernard-Pomier G, Cassuto-Viguier E, Zoccola D, Allieri-Rosenthal M A, Vivinus M, Bernard A
机构信息
Laboratoire d'Immunologie, Hôpital de l'Archet, Nice.
出版信息
Therapie. 1992 Jul-Aug;47(4):293-6.
PMID:1494790
Abstract
The molecule E2 is present on T lymphocytes and thymocytes and is implicated in rosette phenomenon most probably via interaction with CD2. The discrepancy observed between rosette levels and lymphocyte phenotypes in the follow-up of kidney-transplanted patients treated with antilymphocyte globulins (ALG), methylprednisolone and azathioprine leaded us to study the effect of ALG on E2 molecule.
摘要
E2分子存在于T淋巴细胞和胸腺细胞上，很可能通过与CD2相互作用参与玫瑰花结现象。在用抗淋巴细胞球蛋白（ALG）、甲基强的松龙和硫唑嘌呤治疗的肾移植患者随访中观察到的玫瑰花结水平与淋巴细胞表型之间的差异，促使我们研究ALG对E2分子的影响。
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