Nathanson M, Krumholz A, Biddle D
Arch Neurol. 1978 Jul;35(7):448-52. doi: 10.1001/archneur.1978.00500310050010.
Scattered reports, both clinical and experimental, have been accumulating in the past 20 years indicating that true seizures may, indeed, originate from the brain stem and its immediate connections. Four cases are reported that give further strong presumptive evidence that this is so. All the seizures were confined to axial structures (face, tongue, palate, pharynx, diaphragm, and abdomen), and in one case each seizure had an identical "Jacksonian march." The phenomena were documented by 16-mm motion pictures, brain stem signs, and electroencephalography. The EEG consisted of periods of burst activity followed by relative interictal electrocerebral silence.
在过去20年里,临床和实验方面的零散报告不断积累,表明真正的癫痫发作确实可能起源于脑干及其直接连接部位。本文报告了4例病例,进一步有力地提供了支持这一观点的推测性证据。所有发作均局限于轴向结构(面部、舌头、腭、咽部、膈肌和腹部),且在其中1例中,每次发作都有相同的“杰克逊癫痫发作扩展顺序”。这些现象通过16毫米动态影片、脑干体征和脑电图记录下来。脑电图表现为爆发活动期,随后是相对的发作间期脑电静息期。