[Effect of short-term use of omega-3-type polyunsaturated fatty acids in subjects with hypertriglyceridemia].
作者信息
Naber F B, Oudkerk Pool M, Teerlink T, Popp-Snijders C, Gans R O, Bilo H J
机构信息
Afd. Inwendige Geneeskunde, Academisch Ziekenhuis Vrije Universiteit, Amsterdam.
出版信息
Ned Tijdschr Geneeskd. 1992 Aug 1;136(31):1511-4.
OBJECTIVE
To study the effect of omega-3 polyunsaturated fatty acid supplementation on lipid profile in hypertriglyceridaemic patients.
SETTING
General practice.
DESIGN
Prospective, double blind study of 12 weeks' duration.
PATIENTS AND METHODS
Eight patients received fish oil (1800 mg C20: 5 omega-3 eicosapentaenoic acid (EPA) and 1200 mg C22:6 omega-3 docosahexaenoic acid (DHA). Nine patients received corn oil (3000 mg C18: 2 omega-6 linoleic acid daily).
RESULTS
Lipid profile analysis showed a decrease in triglyceride levels after fish oil supplementation. An unexpected and unexplained finding was the rise in total cholesterol and LDH cholesterol with corn oil supplementation.
CONCLUSION
Fish oil causes a decrease in triglyceride levels in hypertriglyceridaemic patients.
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