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[皮肤对致癌物和脱毛剂作用产生反应时表皮抑素活性的变化]

[Change in the activity of epidermal chalones during skin reaction to the effect of a carcinogen and epilation].

作者信息

Ketlinskiĭ S A, Okulov V B

出版信息

Biull Eksp Biol Med. 1978 Mar;85(3):354-6.

PMID:149573
Abstract

The biological activity of an epidermal G2-chalone extracted from the rat back skin was found to decrease 1 to 2 days after the treatment with methylnitrosourea (a carcinogen), and one day after the epilation. Results of quantitative recording and morphological analysis of the skin serving as the source of chalones, pointed to different mechanisms which underlay this effect.

摘要

从大鼠背部皮肤中提取的表皮G2抑素的生物活性,在用甲基亚硝基脲(一种致癌物)处理后1至2天以及脱毛后1天会降低。对作为抑素来源的皮肤进行定量记录和形态学分析的结果,表明了造成这种效应的不同机制。

相似文献

1
[Change in the activity of epidermal chalones during skin reaction to the effect of a carcinogen and epilation].[皮肤对致癌物和脱毛剂作用产生反应时表皮抑素活性的变化]
Biull Eksp Biol Med. 1978 Mar;85(3):354-6.
2
[Purification of epidermal G2-chalone using immunoaffinity chromatography].[利用免疫亲和层析法纯化表皮G2抑素]
Biull Eksp Biol Med. 1983 Aug;96(8):71-3.
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Veroff Pathol. 1975(99):1-67.
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[Effect of an epidermal chalone-containing extract and its fractions on the mitotic activity of stratified epithelia].[含表皮抑素提取物及其组分对复层上皮有丝分裂活性的影响]
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Growth parameters of the hairless mouse epidermis after bleomycin treatment: possible interaction with epidermal chalones.博来霉素治疗后无毛小鼠表皮的生长参数:与表皮抑素的可能相互作用。
Prog Biochem Pharmacol. 1976;11:110-8.
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Effects of methylcholanthrene on epidermal growth regulators. II. Variations in the S-factor.甲基胆蒽对表皮生长调节因子的影响。II. S因子的变化
Beitr Pathol. 1976 Jul;158(2):145-58.
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Variations of mitosis-inhibiting chalone activity in epidermis and dermis after carcinogen treatment.致癌物处理后表皮和真皮中抑制有丝分裂抑素活性的变化。
Cell Tissue Kinet. 1974 May;7(3):251-7. doi: 10.1111/j.1365-2184.1974.tb00905.x.
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[Tissue-specific regulation of proliferative processes in the tissues normally and in pathology: on the problem of chalones].
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[Effect of chalones from liver tissues of intact rats on DNA synthesis and mitotic activity in hepatocytes of regenerating liver].[完整大鼠肝脏组织中抑素对再生肝肝细胞DNA合成及有丝分裂活性的影响]
Vopr Med Khim. 1981 May-Jun;27(3):405-8.