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[大鼠在明暗箱中的行为:位置偏爱任务]

[Rat behavior in a light/dark chamber: place preference task].

作者信息

Shuĭkin N N, Levshina I P, Liperovskaia E V

机构信息

Institute of Higher Nervous Activity and Neurophysiology, Russian Academy of Sciences, Moscow.

出版信息

Zh Vyssh Nerv Deiat Im I P Pavlova. 2003 Nov-Dec;53(6):746-53.

PMID:14959489
Abstract

After a 6-week social isolation (from 22nd to 70th day from birth) male Wistar rats (a sibship, 10 animals), were tested for 20 min in a light/dark box in order to reveal behavioral features of choice of their spatial localization in unknown conditions. Socially deprived rats significantly differed from control animals in longer time of the room choice, higher number of entries of the light section, and higher number of rearings, which was probably explained by their higher anxiety and lack of experience to estimate unexpected stimuli and select a response. The mean level of behavioral activity during exploration of the box defined by the number of elementary operations per minute remained constant and was significantly higher in the socially deprived rats than in the control animals.

摘要

在经历6周的社会隔离(从出生第22天至第70天)后,对一窝10只雄性Wistar大鼠进行测试,将它们置于明暗箱中20分钟,以揭示它们在未知环境中空间定位选择的行为特征。社会剥夺组大鼠与对照组动物相比,在选择房间的时间更长、进入亮区的次数更多以及直立次数更多等方面存在显著差异,这可能是由于它们更高的焦虑水平以及缺乏评估意外刺激和选择应对方式的经验所致。由每分钟基本操作次数定义的探索箱子期间的行为活动平均水平保持恒定,且社会剥夺组大鼠的该水平显著高于对照组动物。

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