Sabetay C, Zaharia B, Pleşea E, Farcaş I, Maloş A, Singer I, Alexandrova T, Alexandrov A
Clinica Chirurgie Pediatrică Spitalul Universitar nr. 1 Craiova.
Chirurgia (Bucur). 2000 Jan-Feb;95(1):29-36.
Presentation of potentially malignant tumours, highly frequently found in children, developed out of embrionary remnants. Study of clinical observation files, iconography resources, histopathological samples and surgical operation notes, corroborated with patient's reexamination several years later. There are presented nine clinic cases of tumours found in newborn, babies and even in young children, with teratome-like structure, that have malignant potential if excised late. Histopathological laboratory tests of the biotic sample are of paramount importance in establishing the structure of the tumour, its malignization abilities and the therapeutical conduct to be adopted. Other useful investigations: radiographs of the vertebral column, abdominal echographs, computerized tomography. Besides sacrococcygian, large and anesthetic, location in newborn, there are presented cases of intra-abdominal teratomes and one case of ovarian teratome. The study also contains a general opinion upon the patients operated on the reexamined several years later.
胚胎残余组织衍生出的潜在恶性肿瘤在儿童中极为常见。对临床观察档案、影像学资料、组织病理学样本及手术记录进行研究，并在数年后对患者进行复查以加以佐证。本文呈现了9例在新生儿、婴儿甚至幼儿中发现的具有畸胎瘤样结构的肿瘤临床病例，若切除过晚则具有恶性潜能。生物样本的组织病理学实验室检测对于确定肿瘤结构、其恶变能力及应采取的治疗方法至关重要。其他有用的检查包括：脊柱X光片、腹部超声、计算机断层扫描。除了新生儿中常见的位于骶尾部、体积较大且需麻醉的肿瘤外，还呈现了腹腔内畸胎瘤病例及1例卵巢畸胎瘤病例。该研究还包含了对数年后接受复查的手术患者的总体评价。
