MMWR Morb Mortal Wkly Rep. 2004 Feb 13;53(5):107-8.
Since the 1988 World Health Assembly resolution to eradicate poliomyelitis, the number of polio-endemic countries has decreased from 125 in 1988 to six in 2003 (i.e., Afghanistan, Egypt, India, Niger, Nigeria, and Pakistan), and the number of cases reported worldwide has decreased from approximately 350,000 to 682. In 2003, approximately 90% of cases were reported from Nigeria (305), India (220), and Pakistan (99); epidemiologic and virologic data demonstrated focal endemic transmission in Afghanistan and Niger, with repeated importations from Pakistan and Nigeria, respectively, and localized transmission in Egypt. On January 15, 2004, the World Health Organization (WHO) released an updated Global Polio Eradication Initiative Strategic Plan outlining activities required to 1) interrupt poliovirus transmission globally, 2) achieve global certification of polio eradication, and 3) prepare for global cessation of childhood vaccination with oral poliovirus vaccine (OPV). The discontinuation of mass vaccination campaigns in the majority of polio-free countries has left these areas vulnerable to importations of wild poliovirus (WPV) from the remaining countries in which polio is endemic. For polio to be eradicated, all remaining poliovirus reservoirs must be eliminated.
自1988年世界卫生大会通过根除脊髓灰质炎的决议以来,脊髓灰质炎流行国家的数量已从1988年的125个减少到2003年的6个(即阿富汗、埃及、印度、尼日尔、尼日利亚和巴基斯坦),全球报告的病例数也从约35万例减少到682例。2003年,约90%的病例报告来自尼日利亚(305例)、印度(220例)和巴基斯坦(99例);流行病学和病毒学数据表明,阿富汗和尼日尔存在局部流行传播,分别反复从巴基斯坦和尼日利亚输入病例,埃及存在局部传播。2004年1月15日,世界卫生组织(WHO)发布了一份更新的全球根除脊髓灰质炎行动战略计划,概述了为以下目标所需开展的活动:1)在全球范围内阻断脊髓灰质炎病毒传播;2)实现全球根除脊髓灰质炎认证;3)为全球停止口服脊髓灰质炎疫苗(OPV)儿童接种做准备。大多数无脊髓灰质炎国家停止大规模疫苗接种活动后,这些地区容易受到来自脊髓灰质炎仍然流行的其余国家的野生脊髓灰质炎病毒(WPV)输入的影响。要根除脊髓灰质炎,必须消除所有剩余的脊髓灰质炎病毒储存宿主。