Salvinelli F, Cancilleri F, Casale M, Luccarelli V, Di Peco V, D'Ascanio L, De Martino A, Denaro V
Areas of Otolaryngology and Orthopedics, University Campus Bio-Medico, Rome, Italy.
Clin Otolaryngol Allied Sci. 2004 Feb;29(1):75-9. doi: 10.1111/j.1365-2273.2004.00783.x.
The aim of the study was to evaluate hearing thresholds in 38 patients with rheumatoid arthritis, divided according to disease activity into active (group A, n = 20) and non-active (group B, n = 18) patients. Pure tone audiometry, tympanometry and complete rheumatological assessment were performed. All patients presented poorer auditory thresholds compared with controls. Patients of group A had both air and bone conduction thresholds poorer than group B (although not statistically significant), and most patients of both groups presented an air-bone (a-b) gap. No significant difference in middle ear pressure was noticed between patients and controls. No correlation between hearing impairment and duration of the disease or patients' age was found. The high prevalence of hearing loss in autoimmune diseases supports the importance of audiometric evaluation in such patients. The auditory recovery through middle ear surgery before cranial nerve involvement could be considered in selected patients. Further investigations are needed for a better knowledge of the middle and inner ear involvement in patients with rheumatoid arthritis.
本研究的目的是评估38例类风湿性关节炎患者的听力阈值,这些患者根据疾病活动度分为活动期(A组,n = 20)和非活动期(B组,n = 18)患者。进行了纯音听力测定、鼓室图检查和全面的风湿病评估。与对照组相比,所有患者的听觉阈值均较差。A组患者的气导和骨导阈值均比B组差(尽管无统计学意义),且两组大多数患者均存在气骨(a-b)差。患者与对照组之间未发现中耳压力有显著差异。未发现听力损害与疾病持续时间或患者年龄之间存在相关性。自身免疫性疾病中听力损失的高患病率支持对此类患者进行听力测定评估的重要性。对于部分患者,可考虑在颅神经受累之前通过中耳手术实现听觉恢复。需要进一步研究以更好地了解类风湿性关节炎患者中耳和内耳受累情况。