Lasso de la Vega Mar, Villarreal Ithzel Maria, Lopez-Moya Julio, Garcia-Berrocal Jose Ramon
"Severo Ochoa" University Hospital, 28911 Madrid, Spain.
"Puerta de Hierro-Majadahonda" University Hospital, 28222 Madrid, Spain.
Scientifica (Cairo). 2016;2016:5713283. doi: 10.1155/2016/5713283. Epub 2016 Apr 27.
Objective. The aim of this study is to analyze the high-frequency hearing levels in patients with rheumatoid arthritis and to determine the relationship between hearing loss, disease duration, and immunological parameters. Materials and Methods. A descriptive cross-sectional study including fifty-three patients with rheumatoid arthritis was performed. The control group consisted of 71 age- and sex-matched patients from the study population (consecutively recruited in Madrid "Area 9," from January 2010 to February 2011). Both a pure tone audiometry and an extended-high-frequency audiometry were performed. Results. Extended-high-frequency audiometry diagnosed sensorineural hearing loss in 69.8% of the patients which exceeded the results obtained with pure tone audiometry (43% of the patients). This study found significant correlations in patients with sensorineural hearing loss related to age, sex, and serum anti-cardiolipin (aCL) antibody levels. Conclusion. Sensorineural hearing loss must be considered within the clinical context of rheumatoid arthritis. Our results demonstrated that an extended-high-frequency audiometry is a useful audiological test that must be performed within the diagnostic and follow-up testing of patients with rheumatoid arthritis, providing further insight into a disease-modifying treatment or a hearing loss preventive treatment.
目的。本研究旨在分析类风湿性关节炎患者的高频听力水平,并确定听力损失、病程和免疫参数之间的关系。材料与方法。进行了一项描述性横断面研究,纳入了53例类风湿性关节炎患者。对照组由71例年龄和性别匹配的研究人群患者组成(2010年1月至2011年2月在马德里“第9区”连续招募)。同时进行了纯音听力测定和扩展高频听力测定。结果。扩展高频听力测定诊断出69.8%的患者存在感音神经性听力损失,这一比例超过了纯音听力测定的结果(43%的患者)。本研究发现,感音神经性听力损失患者的年龄、性别和血清抗心磷脂(aCL)抗体水平之间存在显著相关性。结论。在类风湿性关节炎的临床背景下必须考虑感音神经性听力损失。我们的结果表明,扩展高频听力测定是一种有用的听力学检查,必须在类风湿性关节炎患者的诊断和随访检查中进行,以便进一步了解疾病改善治疗或听力损失预防治疗。