Williams P, Roberts-Harry D, Sandy J
Division of Child Dental Health, University of Bristol Dental School, Lower Maudlin Street, Bristol BS1 2LY.
Br Dent J. 2004 Feb 14;196(3):143-8. doi: 10.1038/sj.bdj.4810935.
Clinical research has previously lacked good methodology and much opinion was based on anecdote which is widely regarded as the weakest form of clinical evidence. There are few randomised control trials in orthodontics which support or refute areas of dogma. The number of randomised control trials is increasing significantly. There is currently however no good evidence that orthodontics causes or cures temporomandibular joint dysfunction, that appropriate extractions in orthodontics ruin patients' profiles, or that the orthodontist is able to significantly influence facial growth with appliances.