Sticher L, Hofsteenge J, Milani A, Neuhaus J M, Meins F
Friedrich Miescher-Institut, Basel, Switzerland.
Science. 1992 Jul 31;257(5070):655-7. doi: 10.1126/science.1496378.
The fungicidal type I chitinases contribute to the defense response of plants against pathogens. Two tobacco chitinases represent a different class of hydroxyproline-containing proteins. Hydroxyproline-rich proteins are predominantly extracellular, structural glycoproteins proteins that lack enzymatic activity and contain many hydroxyproline residues. In contrast, type I chitinases are vacuolar enzymes. They are not glycosylated and contain a small number of hydroxyproline residues restricted to a single, short peptide sequence.
杀菌型I几丁质酶有助于植物对病原体的防御反应。两种烟草几丁质酶代表了一类不同的含羟脯氨酸蛋白。富含羟脯氨酸的蛋白主要是细胞外结构糖蛋白，缺乏酶活性且含有许多羟脯氨酸残基。相比之下，I型几丁质酶是液泡酶。它们不进行糖基化，且仅在一个短肽序列中含有少量羟脯氨酸残基。
