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妇科癌症腹主动脉旁淋巴结的放射治疗:技术、结果及并发症

Radiation therapy of para-aortic lymph nodes in gynaecologic cancers: techniques, results and complications.

作者信息

Carl U M, Bahnsen J, Rapp W

机构信息

Department of Radiation Therapy, University Hospital, Hamburg-Eppendorf.

出版信息

Strahlenther Onkol. 1992 Jul;168(7):383-9.

PMID:1496448
Abstract

From 1965 to 1986 the para-aortic lymph nodes of 141 patients with gynaecologic cancers were irradiated directly after initial treatment of the primary site was completed. Another 32 patients only received para-aortic radiation treatment when para-aortic metastases became clinically apparent some time later. Radiation therapy was performed using a biaxial-four-segmental-rotating-field-technique. Crude survival of the group with initial para-aortic radiation treatment is far better than of the second group. Only five cases of severe complications due to para-aortic treatment were reported. In order to analyze the reason for such a low number of complications, CT-treatment planning for a typical patient was performed for different methods as they have been described in the literature, also referring to treatment data such as success, total dose and dose-distribution, thus influencing the complication rate. Obviously, the biaxial-four-segmental-rotating-field-technique is a method allowing to deposit a certain dose into the target volume without considerably damaging tissues in the vicinity.

摘要

1965年至1986年期间,141例妇科癌症患者在原发部位初始治疗完成后,直接对腹主动脉旁淋巴结进行了照射。另外32例患者仅在一段时间后腹主动脉旁转移在临床上明显时才接受腹主动脉旁放射治疗。放射治疗采用双轴四野旋转技术。初始接受腹主动脉旁放射治疗组的粗生存率远高于第二组。仅报告了5例因腹主动脉旁治疗导致的严重并发症。为了分析并发症数量如此之少的原因,针对文献中描述的不同方法,对一名典型患者进行了CT治疗计划,同时参考了诸如成功率、总剂量和剂量分布等治疗数据,从而影响并发症发生率。显然,双轴四野旋转技术是一种能够在不严重损伤周围组织的情况下,将一定剂量的射线沉积到靶体积内的方法。

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Radiat Oncol. 2019 Dec 26;14(1):236. doi: 10.1186/s13014-019-1442-6.
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Stretching the Limits of Laparoscopy in Gynecological Oncology: Technical Feasibility of doing a Laparoscopic Total Pelvic Exenteration for Palliation in advanced Cervical Cancer.拓展妇科肿瘤腹腔镜手术的极限:晚期宫颈癌姑息性腹腔镜全盆腔脏器切除术的技术可行性
Int J Biomed Sci. 2009 Mar;5(1):17-22.
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Laparoscopic transperitoneal infrarenal para-aortic lymphadenectomy in patients with FIGO stage IB1-II B cervical carcinoma.
FIGO 分期为 IB1-IIB 期宫颈癌患者的腹腔镜经腹肾下主动脉旁淋巴结切除术
JSLS. 2012 Apr-Jun;16(2):229-35. doi: 10.4293/108680812x13427982376266.
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Treatment options in recurrent cervical cancer (Review).复发性宫颈癌的治疗选择(综述)
Oncol Lett. 2010 Jan;1(1):3-11. doi: 10.3892/ol_00000001. Epub 2010 Jan 1.