Starodub N F, Starodub V N
Palladin Institute of Biochemistry, NAS of Ukraine, Kyiv.
Ukr Biokhim Zh (1999). 2002 Jul-Aug;74(4):5-23.
In the review the overall characteristics of biological warfare components, which represent danger to people in the case of their application by military or terrorist groups are discussed. The main part of the review is devoted to modern approaches of antibody obtaining and, in particular, preparation of specific recombinant immunoglobulins as well as to different immune chemical methods of determination of individual toxins and pathogenic microorganisms. A special attention is paid to existing data about the development of rapid, selective, high sensitive, simple and fully automated instrumental methods on the basis of biosensor technology which is designed for the control of components of biological warfare in environmental objects. Additionally industrially manufactured biosensors and their characteristics are given and analyzed.
在这篇综述中，讨论了生物战剂的总体特征，这些生物战剂在被军事或恐怖组织使用时会对人类构成危险。综述的主要部分致力于抗体获取的现代方法，特别是特异性重组免疫球蛋白的制备，以及测定个别毒素和致病微生物的不同免疫化学方法。特别关注了基于生物传感器技术开发的快速、选择性、高灵敏度、简单且完全自动化的仪器方法的现有数据，这些方法旨在检测环境物体中的生物战剂成分。此外，还给出并分析了工业生产的生物传感器及其特性。
