[Features of clinical presentation of malignant adrenocortical tumor cortex metabolism over time].

Malignant adrenocortical tumors is serious oncological pathology, which without early diagnosis and radical, first of all, surgical treatment leads to death. The authors have analyzed the treatment results of 216 patients with adrenocortical carcinomas, which were in clinic during 1968-2002. The tumors were 32.6% of all adrenal tumors. Most of the tumors were hormone-active. The best results were obtained with performing primary radical surgery at the early stages (without appearing of regional metastasis). The performing of reoperations in majority of cases guarantees the remission of disease, but seldom could be radical. The use of chloditan makes longer the survival level, but in the bulk of cases chloditan used as an additional curative method.