Jacobsen Peter, Young Douglas
University of the Pacific, School of Dentistry, 2155 Webster Street, San Francisco, CA 94115, USA.
Spec Care Dentist. 2003 Sep-Oct;23(5):177-9. doi: 10.1111/j.1754-4505.2003.tb00308.x.
Topical fluoride has been the main stay of caries prevention for many decades. There are several mechanisms which make it beneficial including inhibiting demineralization, enhancing remineralization, and inhibiting bacterial growth. Topical fluoride is available in many different forms. The concentrations of various fluoride preparations range from 225 parts per million (ppm) fluoride in over-the-counter oral rinses to 22,600 ppm in the fluoride varnishes. The clinician must decide which type of topical preparation is best suited for their patient. Patients with high caries risk may benefit from prescription strength fluorides (along with the other chemical and dietary therapies described in this issue of Special Care in Dentistry). The application of fluoride varnish is an excellent topical form for those patients who have access to dental care and for whom it is difficult to comply with the use of other topical forms.
几十年来，局部用氟一直是预防龋齿的主要手段。它有多种有益机制，包括抑制脱矿质作用、增强再矿化作用以及抑制细菌生长。局部用氟有多种不同形式。各种氟制剂的浓度范围从非处方口腔漱口液中百万分之225（ppm）的氟化物到氟化物清漆中百万分之22,600的氟化物。临床医生必须决定哪种局部用制剂最适合其患者。高龋齿风险的患者可能会从处方强度的氟化物中受益（以及本期《牙科特殊护理》中描述的其他化学和饮食疗法）。对于那些能获得牙科护理但难以坚持使用其他局部用形式的患者来说，氟化物清漆的应用是一种极好的局部用形式。
