Irwig L, Macaskill P, Houssami N
Screening and Test Evaluation Program, Department of Public Health and Community Medicine, The University of Sydney, Sydney, New South Wales, Australia.
Breast. 2002 Jun;11(3):215-20. doi: 10.1054/brst.2001.0409.
This paper reviews and summarises evidence on the investigation of breast symptoms based on triple testing. The triple test (where any component is positive) has a sensitivity of 99.6%, a specificity of 62%, a likelihood ratio of 2.62 for a positive result, and a likelihood ratio of 0.006 for a negative result. We present measures of test accuracy for the components of the triple test that allow easy estimation of the probability of breast cancer in symptomatic women, given any possible combination of results.
本文回顾并总结了基于三联检测对乳腺症状进行调查的证据。三联检测（任何一个组成部分呈阳性）的敏感度为99.6%，特异度为62%，阳性结果的似然比为2.62，阴性结果的似然比为0.006。我们给出了三联检测各组成部分的检测准确性指标，这些指标能够在已知任何可能的检测结果组合的情况下，方便地估算有症状女性患乳腺癌的概率。
