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全球医疗研发的新贸易框架。

A new trade framework for global healthcare R&D.

作者信息

Hubbard Tim, Love James

机构信息

Wellcome Trust Sanger Institute in Hinxton, United Kingdom.

出版信息

PLoS Biol. 2004 Feb;2(2):E52. doi: 10.1371/journal.pbio.0020052. Epub 2004 Feb 17.

DOI:10.1371/journal.pbio.0020052
PMID:14966544
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC340954/
Abstract

Current business models for drug development are inefficient and ineffective - drugs are not reaching all who need them. Hubbard and Love contend that it is time to explore some alternatives

摘要

当前的药物研发商业模式效率低下且效果不佳——药物无法惠及所有有需要的人。哈伯德和洛夫认为,是时候探索一些替代方案了。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/04d1/340954/b74c0fec7a81/pbio.0020052.g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/04d1/340954/805677982244/pbio.0020052.g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/04d1/340954/b74c0fec7a81/pbio.0020052.g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/04d1/340954/805677982244/pbio.0020052.g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/04d1/340954/b74c0fec7a81/pbio.0020052.g002.jpg

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3
Tropical diseases: raiding the medicine cabinet.
Nature. 2003 Jul 3;424(6944):10-1. doi: 10.1038/424010a.
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Infect Dis Poverty. 2018 Jun 18;7(1):67. doi: 10.1186/s40249-018-0444-1.
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Essential medicines for universal health coverage.全民健康覆盖的基本药物。
Lancet. 2017 Jan 28;389(10067):403-476. doi: 10.1016/S0140-6736(16)31599-9. Epub 2016 Nov 8.
5
Emerging and reemerging neglected tropical diseases: a review of key characteristics, risk factors, and the policy and innovation environment.新出现和再出现的被忽视热带病:关键特征、风险因素以及政策与创新环境综述
Clin Microbiol Rev. 2014 Oct;27(4):949-79. doi: 10.1128/CMR.00045-14.
6
Innovation and access to medicines for neglected populations: could a treaty address a broken pharmaceutical R&D system?为被忽视人群创新和获取药品:一项条约能否解决破碎的药品研发体系?
PLoS Med. 2012;9(5):e1001218. doi: 10.1371/journal.pmed.1001218. Epub 2012 May 15.
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Expert Delphi survey on research and development into drugs for neglected diseases.专家德尔菲调查关于被忽视疾病药物的研发。
BMC Health Serv Res. 2011 Nov 16;11:312. doi: 10.1186/1472-6963-11-312.
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