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Toxicologic evaluation of the new cyclosporin derivative, SDZ IMM 125, in a comparative, subchronic toxicity study in rats.

作者信息

Donatsch P, Mason J, Richardson B P, Ryffel B

机构信息

Preclinical Research, Sandoz Pharma, Ltd, Basel, Switzerland.

出版信息

Transplant Proc. 1992 Aug;24(4 Suppl 2):39-42.

PMID:1496685
Abstract
摘要

相似文献

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Toxicologic evaluation of the new cyclosporin derivative, SDZ IMM 125, in a comparative, subchronic toxicity study in rats.新型环孢素衍生物SDZ IMM 125在大鼠亚慢性毒性对比研究中的毒理学评价
Transplant Proc. 1992 Aug;24(4 Suppl 2):39-42.
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Sites of biotransformation for the cyclosporin derivative SDZ IMM 125 using human liver and kidney slices and intestine. Comparison with rat liver slices and cyclosporin A metabolism.使用人肝切片、肾切片和肠切片对环孢素衍生物SDZ IMM 125进行生物转化的位点。与大鼠肝切片及环孢素A代谢的比较。
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New immunosuppressive agents for pediatric transplantation.用于小儿移植的新型免疫抑制剂
Pediatr Nephrol. 1993 Oct;7(5):567-73. doi: 10.1007/BF00852552.
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In vitro biosynthesis of ring-extended cyclosporins.环扩展环孢菌素的体外生物合成。
Biochem J. 1994 Jun 1;300 ( Pt 2)(Pt 2):395-9. doi: 10.1042/bj3000395.