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Cyclosporine and its analogue SDZ IMM 125 mediate very similar effects on T-cell activation--a comparative analysis in vitro.

作者信息

Baumann G, Andersen E, Quesniaux V, Eberle M K

机构信息

Preclinical Research, Sandoz Pharma Ltd, Basel, Switzerland.

出版信息

Transplant Proc. 1992 Aug;24(4 Suppl 2):43-8.

PMID:1496687
Abstract
摘要

相似文献

1
Cyclosporine and its analogue SDZ IMM 125 mediate very similar effects on T-cell activation--a comparative analysis in vitro.
Transplant Proc. 1992 Aug;24(4 Suppl 2):43-8.
2
Cyclosporine suppression of intracellular activation signal generation is not mediated by prolyl-peptidyl isomerase.
Transplant Proc. 1991 Feb;23(1 Pt 1):323-4.
3
Immunosuppressive activity of [MeBm2t]1-, D-diaminobutyryl-8-, and D-diaminopropyl-8-cyclosporin analogues correlates with inhibition of calcineurin phosphatase activity.[MeBm2t]1-、D-二氨基丁酰基-8-和D-二氨基丙基-8-环孢菌素类似物的免疫抑制活性与钙调神经磷酸酶活性的抑制相关。
J Immunol. 1993 Mar 15;150(6):2139-47.
4
Biology of cyclosporin A and FK506.环孢素A和FK506的生物学特性
Prog Clin Biol Res. 1994;390:203-23.
5
Nuclear association of a T-cell transcription factor blocked by FK-506 and cyclosporin A.
Nature. 1991 Aug 29;352(6338):803-7. doi: 10.1038/352803a0.
6
Study of the immunosuppressive properties of cyclosporine analogues.
Ann N Y Acad Sci. 1993 Jun 23;685:336-8. doi: 10.1111/j.1749-6632.1993.tb35883.x.
7
Covalent binding of cyclosporine inhibits irreversibly T-lymphocyte activation.
Biochem Pharmacol. 1992 Mar 3;43(5):953-60. doi: 10.1016/0006-2952(92)90598-d.
8
Calcium signalling in T cells stimulated by a cyclophilin B-binding protein.亲环素B结合蛋白刺激T细胞中的钙信号传导。
Nature. 1994 Sep 22;371(6495):355-8. doi: 10.1038/371355a0.
9
Effects of cyclolinopeptide A on T lymphocyte activation and peptidyl prolyl isomerase activity.
Biochem Soc Trans. 1996 Feb;24(1):90S. doi: 10.1042/bst024090s.
10
Peptidyl-prolyl cis-trans isomerase is the cyclosporin A-binding protein cyclophilin.肽基脯氨酰顺反异构酶是环孢菌素A结合蛋白亲环蛋白。
Nature. 1989 Feb 2;337(6206):473-5. doi: 10.1038/337473a0.

引用本文的文献

1
Characterization of the Anti-HCV Activities of the New Cyclophilin Inhibitor STG-175.新型亲环素抑制剂STG-175的抗丙型肝炎病毒活性特征
PLoS One. 2016 Apr 22;11(4):e0152036. doi: 10.1371/journal.pone.0152036. eCollection 2016.
2
Crystal structure of calcineurin-cyclophilin-cyclosporin shows common but distinct recognition of immunophilin-drug complexes.钙调神经磷酸酶-亲环蛋白-环孢素的晶体结构显示了对亲免素-药物复合物的共同但不同的识别。
Proc Natl Acad Sci U S A. 2002 Sep 17;99(19):12037-42. doi: 10.1073/pnas.192206699. Epub 2002 Sep 6.
3
Immunosuppressive and nonimmunosuppressive cyclosporine analogs are toxic to the opportunistic fungal pathogen Cryptococcus neoformans via cyclophilin-dependent inhibition of calcineurin.
免疫抑制性和非免疫抑制性环孢素类似物通过亲环蛋白依赖性抑制钙调神经磷酸酶，对机会性真菌病原体新型隐球菌具有毒性。
Antimicrob Agents Chemother. 2000 Jan;44(1):143-9. doi: 10.1128/AAC.44.1.143-149.2000.
4
In vitro biosynthesis of ring-extended cyclosporins.环扩展环孢菌素的体外生物合成。
Biochem J. 1994 Jun 1;300 ( Pt 2)(Pt 2):395-9. doi: 10.1042/bj3000395.
5
Inhibition of human immunodeficiency virus type 1 replication by SDZ NIM 811, a nonimmunosuppressive cyclosporine analog.非免疫抑制性环孢素类似物SDZ NIM 811对1型人类免疫缺陷病毒复制的抑制作用。
Antimicrob Agents Chemother. 1994 Aug;38(8):1763-72. doi: 10.1128/AAC.38.8.1763.