Haddo Omar, Mahroof S, Higgs D, David L, Pringle J, Bayliss M, Cannon S R, Briggs T W R
Bone Tumour Unit, Royal National Orthopaedic Hospital, Stanmore, Middlesex, HA7 4LP, UK.
Knee. 2004 Feb;11(1):51-5. doi: 10.1016/S0968-0160(03)00041-3.
Autologous chondrocyte implantation is a new technique for the treatment of chondral defects in the knee. The exact procedure involved is continuously being developed with the ultimate aim of achieving hyaline cartilage regeneration. We present the outcome of our series of 31 patients, focussing on the use of the chondrogide membrane in the implantation process. Assessment is presented both in the form of arthroscopic appearance at approximately 1 year, and in the form of clinical outcome measures at 1 year and at 2 years after the second stage of the procedure.
the use of chondrogide membrane in the fixation of cells during the implantation process is associated with satisfactory clinical outcome and does not appear to show evidence of hypertrophy at one-year arthroscopy, as compared to periosteum.
自体软骨细胞移植是治疗膝关节软骨缺损的一项新技术。所涉及的确切手术方法正在不断发展,最终目标是实现透明软骨再生。我们展示了我们31例患者系列的结果,重点关注软骨膜在移植过程中的应用。评估以大约1年时的关节镜检查外观形式呈现,以及在手术第二阶段后1年和2年时的临床结果测量形式呈现。
与骨膜相比,在移植过程中使用软骨膜固定细胞与令人满意的临床结果相关,并且在1年关节镜检查时似乎没有肥大的迹象。