Finger Stanley, Koehler Peter J, Jagella Caroline
Department of Psychology, Washington University, St Louis, MO 63130-4899, USA.
Arch Neurol. 2004 Feb;61(2):283-8. doi: 10.1001/archneur.61.2.283.
The idea that damage to one part of the nervous system can have effects at a distance was popular during the 19th century. Constantin von Monakow, MD, accepted this idea and blended it with the newly formulated neuron doctrine early in the 20th century to account for ipsilateral paralyses and recovery of function. He called his theory of neural depression caused by loss of inputs to structures tied to the damaged area diaschisis. In this article, we examine the origins of diaschisis and the goals of Monakow. Credit is given to Monakow for drawing needed attention to the dynamics of the nervous system, remote lesion effects, and recovery of function, even though the fine details or specifics of his theory have had a mixed reception.
19世纪时，神经系统某一部分受损会在远处产生影响的观点颇为流行。医学博士康斯坦丁·冯·莫纳科夫接受了这一观点，并在20世纪初将其与新提出的神经元学说相结合，以解释同侧瘫痪和功能恢复的现象。他将因与受损区域相连的结构输入丧失而导致的神经抑制理论称为“远隔性机能障碍”。在本文中，我们将探讨远隔性机能障碍的起源以及莫纳科夫的研究目标。尽管他理论的细节或具体内容反响不一，但莫纳科夫值得称赞，因为他让人们关注到了神经系统的动态变化、远程损伤效应以及功能恢复。
