Atoum Manar F, Al-Hourani Huda M
Department of Medical Laboratory Sciences, Faculty of Allied Health Sciences, Hashemite University, PO Box 150459, Zarqa 13115, Jordan.
Saudi Med J. 2004 Feb;25(2):168-71.
To compare the risk factors such as age, menopause, menarche, age at the first pregnancy, number of pregnancies and breast feeding period between the familial and non-familial breast cancer females in Jordan.
This study was carried out in Al-Basheer Hospital, Amman, Jordan during the period 2000 and 2002. A questionnaire was used to collect information from 99 females who were histologically and pathologically diagnosed with breast cancer. Data of the questionnaire were entered and analyzed using statistical package for social sciences.
The highest percentage of non-familial and familial breast cancer occurrence was among age group 51-60 years. The age of the first pregnancy is another risk factor of which the highest percentage of breast cancer was reported for both familial (57.1%) and non-familial (65.4) breast cancer females who have their first pregnancy while they were 20-years-old and above. More than 4 pregnancies also represents a risk factor for both non-familial (67.9%) and familial (68.6%) breast cancer patients. In this study, there are no statistical differences between menopause and menarche age among the breast cancer females. Finally, an inverse relationship was shown between breast feeding period (equal or more than 24 months) and the occurrence of breast cancer in both non-familial (2%) and familial (0%) breast cancer.
This study found that age 51-60 years and the increase number of pregnancies (more than 4) in the age of 20 years or more are risk factors for both types of breast cancer. On the other hand, longer period of breast feeding (more than 24 months) decreases the risk of breast cancer in both types.
比较约旦家族性和非家族性乳腺癌女性在年龄、绝经、初潮、首次怀孕年龄、怀孕次数和哺乳期等风险因素方面的差异。
本研究于2000年至2002年期间在约旦安曼的阿尔-巴希尔医院开展。通过问卷调查收集了99名经组织学和病理学诊断为乳腺癌的女性的信息。问卷数据使用社会科学统计软件包进行录入和分析。
非家族性和家族性乳腺癌发生率最高的年龄段为51 - 60岁。首次怀孕年龄是另一个风险因素，首次怀孕时年龄在20岁及以上的家族性（57.1%）和非家族性（65.4%）乳腺癌女性中，该年龄段报告的乳腺癌发生率最高。怀孕超过4次也是非家族性（67.9%）和家族性（68.6%）乳腺癌患者的一个风险因素。在本研究中，乳腺癌女性的绝经年龄和初潮年龄之间没有统计学差异。最后，哺乳期（等于或超过24个月）与非家族性（2%）和家族性（0%）乳腺癌的发生呈负相关。
本研究发现，51 - 60岁以及20岁及以上怀孕次数增加（超过4次）是两种类型乳腺癌的风险因素。另一方面，较长的哺乳期（超过24个月）会降低两种类型乳腺癌的发病风险。
