• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

回顾性分析长期营养性酸负荷儿童生长发育迟缓及尿石症的原因。

Retrospective approach to explain growth retardation and urolithiasis in a child with long-term nutritional acid loading.

作者信息

Manz F, Schmidt H

机构信息

Forschungsinstitut für Kinderernährung, Dortmund.

出版信息

Z Ernahrungswiss. 1992 Jun;31(2):121-9. doi: 10.1007/BF01623070.

DOI:10.1007/BF01623070
PMID:1496830
Abstract

An infant with phenylketonuria unintentionally received a highly acidic low phenylalanine diet for 29 months. Temporary growth retardation and urolithiasis were observed, probably as direct effects of chronic acid loading. Caries at the age of 6 years may be a late consequence. This case report shows that chronic dietary acid load may cause serious side effects.

摘要

一名苯丙酮尿症婴儿意外接受了高酸性低苯丙氨酸饮食29个月。观察到有生长发育迟缓及尿路结石，可能是慢性酸负荷的直接影响。6岁时出现龋齿可能是远期后果。该病例报告表明，慢性饮食酸负荷可能会导致严重的副作用。

相似文献

1
Retrospective approach to explain growth retardation and urolithiasis in a child with long-term nutritional acid loading.回顾性分析长期营养性酸负荷儿童生长发育迟缓及尿石症的原因。
Z Ernahrungswiss. 1992 Jun;31(2):121-9. doi: 10.1007/BF01623070.
2
Methylmalonic aciduria and urolithiasis in a Chinese boy with untreated phenylketonuria.
J Inherit Metab Dis. 1995;18(1):79-80. doi: 10.1007/BF00711379.
3
Evaluation of nutritional status and pathophysiology of growth retardation in patients with phenylketonuria.苯丙酮尿症患者营养状况评估及生长发育迟缓的病理生理学研究
J Inherit Metab Dis. 2003;26(1):1-11. doi: 10.1023/a:1024063726046.
4
Urolithiasis associated with the ketogenic diet.与生酮饮食相关的尿石症。
J Pediatr. 1990 Nov;117(5):743-5. doi: 10.1016/s0022-3476(05)83333-5.
5
Phenylketonuria and its variants.苯丙酮尿症及其变异型。
Prog Med Genet. 1970;7:29-68.
6
[Delayed intrauterine growth with microcephaly in 3 children born of a hyperphenylalaninemic mother].[一位高苯丙氨酸血症母亲所生的3名儿童出现宫内生长迟缓并伴有小头畸形]
Ann Pediatr (Paris). 1972 Apr;19(4):269-76.
7
Maternal phenylketonuria. Detrimental effects on embryogenesis and fetal development.母体苯丙酮尿症。对胚胎发生和胎儿发育的有害影响。
Am J Dis Child. 1969 Dec;118(6):847-58.
8
[Rate of physical development in children with phenylketonuria treated with elimination diet].[采用排除饮食法治疗的苯丙酮尿症患儿的身体发育速率]
Pediatr Pol. 1972 Feb;47(2):159-65.
9
Maternal phenylketonuria: abnormal baby despite low phenylalanine diet during pregnancy.母体苯丙酮尿症：孕期虽采用低苯丙氨酸饮食但仍产下异常婴儿。
Arch Dis Child. 1980 Aug;55(8):634-7. doi: 10.1136/adc.55.8.634.
10
[Incidence of caries in children affected with phenylketonuria].[苯丙酮尿症患儿的龋齿发病率]
Acta Stomatol Croat. 1975;9(2):61-4.

引用本文的文献

1
Adults with Phenylketonuria have suboptimal bone mineral density apart from vitamin D and calcium sufficiency.除维生素D和钙充足外，患有苯丙酮尿症的成年人骨矿物质密度仍不理想。
Front Endocrinol (Lausanne). 2025 Feb 14;16:1488215. doi: 10.3389/fendo.2025.1488215. eCollection 2025.
2
Effects of higher dietary acid load: a narrative review with special emphasis in children.较高膳食酸负荷的影响：特别强调儿童的叙述性综述。
Pediatr Nephrol. 2025 Jan;40(1):25-37. doi: 10.1007/s00467-024-06466-7. Epub 2024 Aug 2.
3
A toddler with Down syndrome, hypercalcaemia, hypercalciuria, medullary nephrocalcinosis and renal failure.

本文引用的文献

1
DISTURBANCES OF HYDROGEN ION BALANCE OCCURRING IN PREMATURE INFANTS. II. LATE METABOLIC ACIDOSIS.早产儿中发生的氢离子平衡紊乱。II. 晚期代谢性酸中毒。
Acta Paediatr (Stockh). 1964 Nov;53:517-26. doi: 10.1111/j.1651-2227.1964.tb07263.x.
2
[Renal acid excretion and renal molar load in healthy children and adults].
Monatsschr Kinderheilkd. 1984 Mar;132(3):163-7.
3
Acid-base homeostasis of low-birth-weight and full-term infants in early life.低体重和足月婴儿早期的酸碱平衡
Pediatr Nephrol. 1996 Apr;10(2):251. doi: 10.1007/BF00862098.
J Pediatr Gastroenterol Nutr. 1983;2 Suppl 1:S99-107. doi: 10.1097/00005176-198300201-00013.
4
Standards from birth to maturity for height, weight, height velocity, and weight velocity: British children, 1965. II.1965年英国儿童从出生到成年的身高、体重、身高增长速度和体重增长速度标准：第二部分。
Arch Dis Child. 1966 Dec;41(220):613-35. doi: 10.1136/adc.41.220.613.
5
Retention of radiostrontium, strontium, calcium, and phosphorus by infants. Appendix A-H.婴儿对放射性锶、锶、钙和磷的潴留。附录A - H。
Pediatrics. 1969 Apr;43(4):733-56.
6
The renal response of children to acute ammonium chloride acidosis.儿童对急性氯化铵酸中毒的肾脏反应。
Pediatr Res. 1967 Nov;1(6):452-60. doi: 10.1203/00006450-196711000-00004.
7
Metabolic acidosis resulting from intravenous alimentation mixtures containing synthetic amino acids.由含合成氨基酸的静脉营养混合液引起的代谢性酸中毒。
N Engl J Med. 1972 Nov 9;287(19):943-8. doi: 10.1056/NEJM197211092871901.
8
Dietary treatment of inborn errors of amino acid and carbohydrate metabolism.氨基酸和碳水化合物代谢先天性疾病的饮食治疗
Bibl Nutr Dieta. 1973(18):181-201. doi: 10.1159/000393052.
9
Ammonium urate urinary stones.尿酸铵尿路结石
Urol Res. 1986;14(6):315-8. doi: 10.1007/BF00262382.
10
Suboptimal mineral composition of cow's milk formulas: a risk factor for the development of late metabolic acidosis.
Acta Paediatr Scand. 1990 Aug-Sep;79(8-9):743-9. doi: 10.1111/j.1651-2227.1990.tb11549.x.