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[使用免疫球蛋白红细胞制剂进行假结核病早期实验室诊断的经验]

[Experience with the use of an immunoglobulin erythrocyte preparation for the early laboratory diagnosis of pseudotuberculosis].

作者信息

Dulatova M V, Antonov V S, Golovacheva S N, Goloveshkina T N, Alkhazov Iu M, Volodina I K

出版信息

Zh Mikrobiol Epidemiol Immunobiol. 1992 Apr(4):55-7.

PMID:1496881
Abstract

An immunoglobulin erythrocytic preparation for the rapid detection of Yersinia pseudotuberculosis was developed. The preparation was shown to be specific and sufficiently sensitive (8 x 10(5) microbial cells/ml). The preparation was used for the examination of 102 patients; in 62 of these patients the diagnosis was confirmed by means of common laboratory and clinical methods. Y. pseudotuberculosis antigen was detected in the blood of 39 patients (63%), and in 12 patients (29.4%) the results of traditional laboratory tests were negative. In 19 out of 23 patients the coincidence of the results of bacteriological and seroindication study was registered. During the study of the remaining 40 patients the antigen was detected only in 6 patients, including 3 patients with enteric yersiniosis.

摘要

研制出一种用于快速检测假结核耶尔森菌的免疫球蛋白红细胞制剂。该制剂具有特异性且灵敏度足够(8×10⁵个微生物细胞/毫升)。用该制剂对102例患者进行检测;其中62例患者通过常规实验室和临床方法确诊。在39例患者(63%)的血液中检测到假结核耶尔森菌抗原,12例患者(29.4%)传统实验室检测结果为阴性。23例患者中有19例细菌学和血清学检测结果相符。在对其余40例患者的研究中,仅在6例患者中检测到抗原,其中包括3例肠道耶尔森菌病患者。

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