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毒蛇咬伤:过去、现在及未来的治疗选择

Venomous snakebite: past, present, and future treatment options.

作者信息

Blackman J R, Dillon S

机构信息

Family Practice Residency of Idaho, Boise 83704.

出版信息

J Am Board Fam Pract. 1992 Jul-Aug;5(4):399-405.

PMID:1496896
Abstract

BACKGROUND

Venomous snakebites continue to cause great morbidity, and treatment options are confusing the attending physician. In the United States approximately 45,000 snakebites occur each year, of which some 8000 are by 20 species of venomous snakes.

METHODS

Information on venomous snakes and snakebite treatment was gathered from the libraries of the Wilderness Medical Society and the Rocky Mountain Center for Wilderness Medicine in Boise, Idaho (co-supported by the Boise State University and the Family Practice Residency of Idaho), as well as from current literature files of physicians practicing wilderness medicine.

RESULTS AND CONCLUSIONS

Three genera of venomous snakes account for the majority of poisonous snake envenomations in this country. Most hospitalized victims are bitten either by rattlesnakes or copperheads or by unidentified snakes. Most of these bites occur during the summer months and are found on the extremities. Field treatment focuses on the application of a vacuum extractor and transportation to the nearest medical facility. Although constriction band use can be helpful, tourniquets, incision and suction, and ice therapy are contraindicated. Electric shock therapy is of no use and could cause serious injury. Hospital management focuses on rapid clinical evaluation and laboratory tests to establish the degree of envenomation, looking for clotting abnormalities. If envenomation has occurred and is reactive, polyvalent antivenin should be administered according to the degree of envenomation. Errors in diagnosis and treatment result in increased morbidity and put attending physicians at risk for litigation. Prevention remains the most successful approach to snakebite management.

摘要

背景

毒蛇咬伤持续导致严重的发病情况,治疗选择让主治医生感到困惑。在美国,每年约发生45000起蛇咬伤事件,其中约8000起是由20种毒蛇造成的。

方法

从荒野医学会图书馆以及爱达荷州博伊西的落基山荒野医学中心(由博伊西州立大学和爱达荷州家庭医学住院医师项目共同支持)收集有关毒蛇和蛇咬伤治疗的信息,同时也从从事荒野医学的医生的当前文献档案中收集。

结果与结论

该国大多数毒蛇咬伤中毒事件是由三个属的毒蛇造成的。大多数住院受害者被响尾蛇、铜头蛇或不明种类的蛇咬伤。这些咬伤大多发生在夏季,且多在四肢。现场治疗重点是应用真空吸引器并转运至最近的医疗机构。虽然使用压迫带可能有帮助,但止血带、切开吸引和冰敷疗法是禁忌的。电击疗法无效且可能导致严重伤害。医院管理重点是进行快速临床评估和实验室检查以确定中毒程度,查找凝血异常情况。如果发生中毒且有反应,应根据中毒程度给予多价抗蛇毒血清。诊断和治疗错误会导致发病率增加,并使主治医生面临诉讼风险。预防仍然是蛇咬伤管理最成功的方法。

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