Skoczyńska Anna, Hryniewicz Waleria
Pol Merkur Lekarski. 2003 Nov;15(89):459-62.
In spite of the progress in antibiotic therapy and immunoprophylaxis Neisseria meningitidis remains one of the major causes of meningitis and sepsis burdened by high mortality. In this paper characteristics of N. meningitidis and in particular its epidemiology, virulence factors, antibiotic therapy and resistance mechanisms, immuno- and chemoprophylaxis, are discussed. Data from the National Reference Centre for Bacterial Meningitis are also presented. These data indicate that this pathogen is the most common laboratory confirmed bacterial etiologic agent of community-acquired meningitis in Poland.
尽管在抗生素治疗和免疫预防方面取得了进展，但脑膜炎奈瑟菌仍然是脑膜炎和败血症的主要病因之一，死亡率很高。本文讨论了脑膜炎奈瑟菌的特征，特别是其流行病学、毒力因子、抗生素治疗和耐药机制、免疫预防和化学预防。还介绍了国家细菌性脑膜炎参考中心的数据。这些数据表明，在波兰，这种病原体是社区获得性脑膜炎最常见的实验室确诊细菌病原体。
