Shoukri M M, Asyali M H, Walter S D
Department of Biostatistics, Epidemiology and Scientific Computing, King Faisal Specialist Hospital and Research Center, P.O. Box 3354, Riyadh, Saudi Arabia.
Biometrics. 2003 Dec;59(4):1107-12. doi: 10.1111/j.0006-341x.2003.00127.x.
Reliability of continuous and dichotomous responses is usually assessed by means of the intraclass correlation coefficient (ICC). We derive the optimal allocation of the number of subjects k and the number of repeated measurements n that minimize the variance of the estimated ICC. Cost constraints are discussed for the case of normally distributed responses. Tables showing optimal choices of k and n are given, along with guidelines for the design of reliability studies in light of our results and those reported by others.
连续型和二分法反应的可靠性通常通过组内相关系数（ICC）来评估。我们推导出了受试者数量k和重复测量次数n的最优分配，以使估计的ICC方差最小化。针对正态分布反应的情况讨论了成本约束。给出了显示k和n最优选择的表格，以及根据我们的结果和其他人报告的结果进行可靠性研究设计的指南。
