Rosen M G, Dickinson J C
Department of Obstetrics and Gynecology, Sloane Hospital for Women of Columbia Presbyterian Medical Center, New York, New York.
Am J Obstet Gynecol. 1992 Aug;167(2):417-23. doi: 10.1016/s0002-9378(11)91422-7.
The clinician is often held responsible for obstetric events that are suspected of being related to cerebral palsy. To review the incidence of cerebral palsy and to aid the clinician in this situation, a search of published studies was conducted. Composite rates of cerebral palsy in different birth weight infants and cerebral palsy with and without serious mental retardation were calculated. The cumulative incidence rate at the age of 5 to 7 years was 2.7 cases of cerebral palsy for 1000 birth cohorts. Approximately 36% of all cerebral palsy occurred in the infant less than 2500 gm. Serious mental retardation (intelligence quotient less than 50) accompanied cerebral palsy approximately 30% of the time for the term infant and 18% of the time when the infant was less than 2500 gm. On the basis of a past estimation that 70% of cerebral palsy is of antepartum or unknown origin, the term infant at risk for intrapartum-attributed cerebral palsy may be about 1 in 2000 term births.
临床医生常常要对疑似与脑瘫有关的产科事件负责。为了回顾脑瘫的发病率并在这种情况下帮助临床医生，我们对已发表的研究进行了检索。计算了不同出生体重婴儿的脑瘫综合发生率以及伴有和不伴有严重智力发育迟缓的脑瘫发生率。5至7岁时的累积发病率为每1000例出生队列中有2.7例脑瘫。所有脑瘫病例中约36%发生在体重不足2500克的婴儿中。足月婴儿中约30%的脑瘫伴有严重智力发育迟缓（智商低于50），而体重不足2500克的婴儿中这一比例为18%。根据过去的估计，70%的脑瘫源于产前或病因不明，因此足月分娩中因产时因素导致脑瘫的风险约为每2000例足月分娩中有1例。
