Ing Malcolm R, Rezentes Kau'i
Division of Ophthalmology, Deparment of Surgery, John A. Burns School of Medicine, University of Hawaii, Honolulu, HI 96826, USA.
J AAPOS. 2004 Feb;8(1):35-7. doi: 10.1016/j.jaapos.2003.08.012.
The results of recent studies have shown that the presence and quality of stereopsis in patients with congenital esotropia and subsequent surgically alignment are dependent upon the duration of the misalignment during the first 2 years of life. The purpose of this study was to investigate the presence of fusion in patients with different durations of misalignment whose eyes were aligned at different ages by age 2 years.
Data previously obtained in a study of 90 patients with congenital esotropia aligned by 2 years of age, examined in a masked independent evaluation for binocularity, were analyzed. Patient age at alignment and duration of misalignment were correlated with the presence of fusion.
Fusion was present in 94% of all patients aligned by age 2 years and in 94% of patients with < or =21 months of misalignment. There was no statistically significant difference between those aligned by 6, 12, or 24 months (P > 0.05, power = 0.8). No significant difference was found between those aligned with duration of misalignment < or = 6, between 7 and 12, or between 13 and 21 months.
Unlike the findings of stereopsis studies, there was no significant difference in the proportion of patients who achieved fusion in congenital esotropes who had up to 21 months of misalignment and whose eyes were aligned at different ages within the first 24 months of life.
近期研究结果表明，先天性内斜视患者的立体视存在情况及质量，以及后续手术矫正后的情况，取决于出生后头2年眼位偏斜的持续时间。本研究的目的是调查不同眼位偏斜持续时间的患者在2岁前不同年龄实现眼位矫正后融合的情况。
分析之前一项对90例2岁前实现眼位矫正的先天性内斜视患者的研究数据，这些患者接受了双眼视的盲法独立评估。眼位矫正时的患者年龄和眼位偏斜持续时间与融合的存在情况相关。
在所有2岁前实现眼位矫正的患者中，94%存在融合；在眼位偏斜≤21个月的患者中，94%存在融合。6个月、12个月或24个月实现眼位矫正的患者之间无统计学显著差异（P>0.05，检验效能=0.8）。眼位偏斜持续时间≤6个月、7至12个月或13至21个月实现眼位矫正的患者之间未发现显著差异。
与立体视研究结果不同，在出生后头24个月内不同年龄实现眼位矫正、眼位偏斜持续时间长达21个月的先天性内斜视患者中，实现融合的患者比例无显著差异。
