Henry J F, Misso C, Sebag F, Iacobone M
Service de Chirurgie Generale et Endocrinienne, Chu Timone, Università di Marsiglia, Francia.
Ann Ital Chir. 2003 Jul-Aug;74(4):401-5.
Different minimally invasive techniques of parathyroidectomy have been described. We performed a retrospective study to evaluate the indications and results of video-assisted parathyroidectomy (VAP) in the management of patients with primary hyperparathyroidism (PHPT).
Between 1998 and 2002, 528 patients were operated on because PHPT. VAP was proposed for patients with sporadic PHPT, without associated goiter and previous neck surgery, in whom a single adenoma was localized. VAP was performed by lateral approach with insufflation for patients with adenoma located deeply in the neck and by gasless midline approach for anteriorly located adenomas. A quick parathyroid (qPTH) assay was used during the surgical procedure. Calcemia, phosphoremia and PTH were systematically evaluated after surgery.
Of 528 patients with PHPT, 228 (43%) were not eligible for VAP because associated nodular goiter (99 cases), previous neck surgery (42 cases), suspicion of multiglandular disease (25 cases), lack of preoperative localization (48 cases), and miscellaneous causes (14 cases). VAP was performed in 300 patients with sporadic PHPT: 282 lateral access, 17 midline access and one thoracoscopy. Mean operative time was 50'. Conversion to conventional parathyroidectomy was required in 14% of cases. One patient presented a definitive recurrent nerve palsy. One persistent and one recurrent PHPT were observed.
VAP can be proposed for patients with PHPT. Immediate results of VAP are similar to those obtained with conventional parathyroidectomy; no conclusions can be drawn in terms of influence of VAP on the outcome of the patients operated for PHPT.
已描述了不同的甲状旁腺切除术微创技术。我们进行了一项回顾性研究,以评估电视辅助甲状旁腺切除术(VAP)在原发性甲状旁腺功能亢进症(PHPT)患者管理中的适应证和结果。
1998年至2002年间,528例患者因PHPT接受手术。对于散发性PHPT、无相关甲状腺肿且既往无颈部手术史、单个腺瘤定位明确的患者,建议采用VAP。对于腺瘤位于颈部深处的患者,通过侧方入路并充气进行VAP;对于位于前方的腺瘤,采用无气中线入路。手术过程中使用快速甲状旁腺(qPTH)检测。术后系统评估血钙、血磷和甲状旁腺激素(PTH)。
528例PHPT患者中,228例(43%)不符合VAP标准,原因包括相关结节性甲状腺肿(99例)、既往颈部手术史(42例)、怀疑多腺体疾病(25例)、术前未定位(48例)及其他原因(14例)。300例散发性PHPT患者接受了VAP:282例采用侧方入路,17例采用中线入路,1例采用胸腔镜入路。平均手术时间为50分钟。14%的病例需要转为传统甲状旁腺切除术。1例患者出现永久性喉返神经麻痹。观察到1例持续性和1例复发性PHPT。
PHPT患者可考虑采用VAP。VAP的近期结果与传统甲状旁腺切除术相似;就VAP对接受PHPT手术患者的预后影响而言,尚无定论。