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原发性甲状旁腺功能亢进症的微创甲状旁腺切除术的多样化:微创电视辅助甲状旁腺切除术和局部麻醉下的微创开放电视放大甲状旁腺切除术。

Diversification of minimally invasive parathyroidectomy for primary hyperparathyroidism: minimally invasive video-assisted parathyroidectomy and minimally invasive open videoscopically magnified parathyroidectomy with local anesthesia.

作者信息

Lorenz Kerstin, Phuong Nguyen-Thanh, Dralle Henning

机构信息

Department of Surgery, University of Halle-Wittenberg, Ernst-Grube-Strasse 40, 06120 Halle/Saale, Germany.

出版信息

World J Surg. 2002 Aug;26(8):1066-70. doi: 10.1007/s00268-002-6672-2. Epub 2002 Jun 6.

Abstract

With the expansion of minimally invasive parathyroid surgery for primary hyperparathyroidism, new approaches and techniques evolved, creating new surgical algorithms with consequences for indication for surgery and patient selection. The presented methods of selective, minimally invasive parathyroidectomy represent this development of diversification. Minimally invasive video-assisted parathyroidectomy (MIVAP) has advanced to bilateral exploration, avoiding preoperative localization other than ultrasonography. Furthermore, a new technique of minimally invasive open parathyroidectomy with the option of videoscopic magnification under local anesthesia (MIPLA) for localizable adenomas is introduced. A series of 103 patients were operated on for primary hyperparathyroidism using minimally invasive procedures: 87 with MIVAP and 16 with MIPLA. With MIVAP the conversion rate to cervicotomy for multiglandular disease or technical difficulties was 16% (n = 14). With MIPLA, conversion to general intubation anesthesia or additional sedation was necessary in four patients. A transient laryngeal nerve palsy was observed in one patient with MIVAP. Bilateral exploration was carried out during 29 MIVAPs and 2 MIPLAs. The duration of surgery differed, with a median 63 minutes for MIVAP and 39 minutes for MIPLA. Surgery under local anesthesia was completed in 4 patients with MIVAP and in 14 with MIPLA. All patients were cured of primary hyperparathyroidism. Preliminary results of diversified procedures demonstrate effects regarding omission of preoperative diagnostics, overall cost reduction, and increasing patient selection for selective parathyroid surgery because of primary hyperparathyroidism.

摘要

随着原发性甲状旁腺功能亢进症微创甲状旁腺手术的扩展,新的方法和技术不断发展,产生了新的手术算法,对手术指征和患者选择产生了影响。所介绍的选择性微创甲状旁腺切除术方法代表了这种多样化的发展。微创视频辅助甲状旁腺切除术(MIVAP)已发展到双侧探查,除超声检查外无需术前定位。此外,还引入了一种新的微创开放性甲状旁腺切除术技术,即对于可定位腺瘤可在局部麻醉下选择视频放大(MIPLA)。对103例原发性甲状旁腺功能亢进症患者采用微创方法进行手术:87例采用MIVAP,16例采用MIPLA。采用MIVAP时,因多腺疾病或技术困难而转为颈部切开术的转化率为16%(n = 14)。采用MIPLA时,4例患者需要转为全身插管麻醉或额外镇静。1例MIVAP患者出现短暂性喉返神经麻痹。29例MIVAP和2例MIPLA手术中进行了双侧探查。手术时间不同,MIVAP的中位时间为63分钟,MIPLA为39分钟。4例MIVAP患者和14例MIPLA患者在局部麻醉下完成手术。所有患者的原发性甲状旁腺功能亢进症均得到治愈。多样化手术的初步结果表明,在省略术前诊断、总体成本降低以及因原发性甲状旁腺功能亢进症而增加选择性甲状旁腺手术的患者选择方面有效果。

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