Price J, Grudzinski A W, Craswell P W, Thomas B J
Department of Psychiatry, University of Queensland, Royal Brisbane Hospital, Australia.
Arch Environ Health. 1992 Jul-Aug;47(4):256-62. doi: 10.1080/00039896.1992.9938358.
Bone lead levels (finger and tibia) were measured, both in vivo and in vitro, with an x-ray fluorescence technique. In vivo finger-bone lead levels of 105 volunteers were estimated and subsequently re-estimated after a 5-y period. In many instances, elevated levels in some of these individuals probably resulted from lead ingested during childhood (i.e., more than 60 y ago). A decline in finger-bone lead from the initial value was accompanied by a mean finger-bone lead half-life of 6.2 y (n = 25); many individual's half-life values were less than 3.0 y. Perhaps one reason for these low values is the special propensity of finger bone to resorption during the involutional period, at which time there are high levels of circulating parathormone.
采用X射线荧光技术在体内和体外测量了骨铅水平（手指和胫骨）。对105名志愿者的体内手指骨铅水平进行了估计，并在5年后再次进行估计。在许多情况下，这些个体中一些人的铅水平升高可能是由于儿童时期（即60多年前）摄入的铅所致。手指骨铅水平从初始值下降，其平均手指骨铅半衰期为6.2年（n = 25）；许多个体的半衰期值小于3.0年。这些低值的一个可能原因是在 involutional 期手指骨对吸收的特殊倾向，此时循环甲状旁腺激素水平较高。
