Mariani R, Coussement A, Berard E, Altar S, el Barbary M
Service de Pédiatrie, Hôpital de Cimiez, Nice.
Arch Fr Pediatr. 1992 Apr;49(4):345-50.
Magnetic resonance imaging (MRI) of the sellar and juxta sellar area was performed in 40 children with idiopathic hypopituitarism. MRI was normal in the 17 patients with partial growth hormone (GH) deficiency and in the 5 patients with GH neurosecretory dysfunction. Among the 18 patients with complete GH deficiency, the 10 with pituitary stalk transection presented more often with perinatal abnormalities, had the most severe GH deficiencies and more frequently multiple hormone deficiencies, in particular TSH deficiency. Pituitary gland size studies showed that the small size of the residual glandular tissue was responsible for these particularities. If MRI is of no great interest for functional GH deficiency, in half of the primary complete GH deficiencies, it enables to visualize a pituitary stalk transection with regeneration of neurohypophysis.
对40例特发性垂体功能减退症患儿进行了鞍区及鞍旁区域的磁共振成像（MRI）检查。17例部分生长激素（GH）缺乏症患者和5例GH神经分泌功能障碍患者的MRI结果正常。在18例完全性GH缺乏症患者中，10例垂体柄横断患者围产期异常更为常见，GH缺乏最为严重，且更常出现多种激素缺乏，尤其是促甲状腺激素（TSH）缺乏。垂体大小研究表明，残留腺组织体积小是导致这些特殊性的原因。如果MRI对功能性GH缺乏症意义不大，那么在一半的原发性完全性GH缺乏症中，它能够显示垂体柄横断及神经垂体再生情况。
