Waniewski Jacek
Instytut Biocybernetyki i Inzynierii Biomedycznej PAN, Warszawa.
Pol Merkur Lekarski. 2003 Oct;15(88):316-8.
Three types of mathematical models of peritoneal transport are reviewed: distributed models, membrane models, and pore models. The distributed model described the capillary bed distributed within the tissue with two sets of transport parameters for the capillary wall and for the tissue separately. The membrane and the three pore models consider blood as a compartment separated by a transport barrier from the dialysis fluid in the peritoneal cavity. The membrane model describes the barrier using "black box" transport parameters, whereas the three pore model assumes three types of pores across the barrier (large, small, and ultra small pores) and a mathematical theory of fluid and solute transport through the pore. Each model contributes its specific share to investigations of peritoneal transport. The basic features and specific areas of application of all three types of the models are discussed.
分布模型、膜模型和孔隙模型。分布模型描述了分布在组织内的毛细血管床，分别为毛细血管壁和组织设置了两组转运参数。膜模型和三种孔隙模型将血液视为一个隔室，通过一个转运屏障与腹膜腔内的透析液分隔开。膜模型使用“黑箱”转运参数来描述屏障，而三种孔隙模型假定屏障上存在三种类型的孔隙（大孔、小孔和超小孔）以及一种流体和溶质通过孔隙转运的数学理论。每种模型在腹膜转运研究中都有其特定的贡献。本文讨论了所有这三种类型模型的基本特征和特定应用领域。
