Bloom P A, Ferris J D, Laidlaw D A, Goddard P R
Department of Ophthalmology, Bristol Eye Hospital, England.
Arch Ophthalmol. 1992 Aug;110(8):1105-11. doi: 10.1001/archopht.1992.01080200085030.
Fifteen patients with uveal malignant melanomas were studied by magnetic resonance imaging. The magnetic resonance imaging appearances varied from those that have been reported previously to be characteristic of these tumors. In our series, malignant melanomas were of high signal on the T1 sequence and of variable but usually also of high signal on the T2 and Short Tau Inversion Recovery (STIR) sequences, a signal combination rarely described before. We postulate that magnetic resonance imaging appearances may be dependent on variations in histologic factors and on the type and field strength of the scanner used. It is widely believed that the paramagnetic melanin in malignant melanomas gives these tumors characteristic magnetic resonance imaging appearances, but our finding of diverse magnetic resonance imaging appearances for proved malignant melanomas suggests that this may not always be the case. We advise caution in diagnosing malignant melanomas from magnetic resonance imaging appearances alone.
对15例葡萄膜恶性黑色素瘤患者进行了磁共振成像研究。磁共振成像表现与先前报道的这些肿瘤的特征有所不同。在我们的研究系列中，恶性黑色素瘤在T1序列上呈高信号，在T2和短tau反转恢复（STIR）序列上信号可变但通常也呈高信号，这种信号组合以前很少被描述。我们推测，磁共振成像表现可能取决于组织学因素的变化以及所使用扫描仪的类型和场强。人们普遍认为，恶性黑色素瘤中的顺磁性黑色素赋予这些肿瘤特征性的磁共振成像表现，但我们对已证实的恶性黑色素瘤的多种磁共振成像表现的发现表明情况可能并非总是如此。我们建议仅根据磁共振成像表现诊断恶性黑色素瘤时要谨慎。
