Kuzniecky Ruben I, Guthrie Barton L
UAB Epilepsy Center, Department of Neurology, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Epileptic Disord. 2003 Dec;5(4):275-80.
Hypothalamic hamartomas are often associated to a progressive epileptic encephalopathy. Non-invasive data indicates that destruction or isolation of the hamartoma may stop seizures. We present data on patients who underwent stereotactic radiofrequency with or without endoscopy. Epilepsy improved in 60% of patients with minimal morbidity. This approach was less successful in large lesions. These results indicate that this approach should be considered in patients with small/medium lesions.
下丘脑错构瘤常与进行性癫痫性脑病相关。非侵入性数据表明，错构瘤的破坏或隔离可能会停止癫痫发作。我们展示了接受立体定向射频治疗（有或无内镜检查）的患者的数据。60%的患者癫痫症状得到改善，且发病率极低。这种方法对大病灶的治疗效果较差。这些结果表明，对于中小病灶的患者应考虑采用这种方法。
